The Irrationality of GOF Avian Influenza Virus Research

The Irrationality of GOF Avian Influenza Virus Research

The last two and a half years have witnessed a curious debate in virology characterized by a remarkable lack of discussion. It goes by the misleading epithet "gain of function" (GOF) influenza virus research, or simply GOF. As will be seen, there is nothing good to be gained. The controversial experiments confer aerosol transmission on avian influenza virus strains that can infect humans, but w...

Evaluating the Immunogenicity of Avian Influenza Virus Nucleoprotein

  Background:  Influenza viruses cause Avian Influenza (AI) is a serious infectious disease belonging to type A Orthomyxovirus. A viral RNA synthesis is due to an interaction of the nucleoprotein (NP) with the viral polymerase. In the present study, we have evaluated the immunogenicity of avian influenza virus nucleoprotein.  Materials & Methods:   An Influenza Virus N9H2 subtype A/Chicken I...

Standardization of ELISA for Detection of Avian Influenza Virus Antibodies

Isolation and Identification of Avian Influenza Virus H9N2 Subtype

Optimizing the process of inactivating influenza virus subtype H9N2 by formalin in the production of killed avian influenza vaccine

Avian influenza is one of the most important diseases in avian industry, which also threats human population. Thus, vaccination is necessary for controlling this viral disease. In this study, killed vaccine of avian influenza subtype H9N2 and formalin solution (for virus inactivation) were used. It is necessary to study the effect of different factors such as formalin concentration, as well as ...